April 11, 2009 |
Asthma patients using powerful acid-reflux drugs even though they don't have heartburn should stop taking them, lung experts say. The medicine doesn't improve asthma symptoms, as had been thought. A study published in Thursday's New England Journal of Medicine found that among 412 patients with poorly controlled asthma, the group given the proton pump inhibitor Nexium twice a day for six months fared no better in symptom control than patients getting placebos.
February 26, 2008 |
AstraZeneca won a fight with Walgreen Co., Rite Aid Corp. and three other drug sellers that had accused the pharmaceutical company of breaking the law by how it marketed its blockbuster heartburn medication Nexium. The U.S. District Court for the District of Columbia dismissed the complaints and ruled that Walgreen, Rite Aid, Meijer Inc., Louisiana Wholesale Drug and Burlington Drug Co. had failed to show that London-based AstraZeneca violated antitrust law. The drug sellers had accused AstraZeneca of breaking the law by trying to protect its sales by switching its marketing efforts from Prilosec to the more expensive Nexium and an over-the-counter version of Prilosec months before Prilosec's patent expired in 2001.
November 1, 2010 |
I take zolpidem (Ambien) for insomnia. It helps me fall asleep but not stay asleep, and it gives me a dry mouth. My doctor suggested I try melatonin instead to prolong the time I stay asleep. Does that sound reasonable? The studies on melatonin are mixed. A double-blind French study published this summer in the journal BMC Complementary and Alternative Medicine found no benefit. It appears to be more useful for jet lag, according to a report in the September issue of Current Treatment Options in Neurology.
March 3, 2011 |
Beware the possible downside of those prescription proton pump inhibitors, more commonly known as Nexium, Prilosec, Prevacid, etc., that are often prescribed for gastroesophageal reflux disease or stomach ulcers. They apparently can do a number on your magnesium levels. The Food and Drug Administration warned Wednesday that the drugs can eventually lead to low serum magnesium levels, or hypomagnesemia, when taken for more than a year. Got that? Hypomagnesemia. In other words: Too little magnesium.
December 11, 2007 |
U.S. regulators said Monday that they had cleared AstraZeneca's bestselling heartburn drugs Prilosec and Nexium of links to heart problems, but disclosed a review of a potential risk of hip fractures. The Food and Drug Administration concluded the drugs had no negative effect on the heart, an issue under scrutiny after two small studies suggested a greater risk of heart attacks, heart failure and heart-related sudden death from the drugs than from surgery to remedy severe acid reflux disease.
August 10, 2007 |
Federal regulators said Thursday that they had opened a safety investigation of two popular heartburn drugs -- Nexium, widely marketed as the "purple pill," and Prilosec, its older chemical cousin -- after receiving clinical data that appeared to link them to serious heart problems. But the Food and Drug Administration emphasized that it had found no firm evidence of such a connection, and advised doctors and patients not to change medication practices.