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African American smokers have higher levels of the metabolized form of nicotine in their bodies than do white smokers, providing potential clues about why blacks are less likely to quit smoking and more likely to develop lung cancer than whites, according to a study of more than 2,000 people by federal researchers published today in the Journal of the American Medical Assn.
March 29, 1998 | Reuters
Mouthing, chewing or sucking on an unlit cigar can still deliver a heavy nicotine punch, a Johns Hopkins School of Medicine researcher said Saturday. "If you're sucking on a cigar when the pH [alkalinity] is high enough, you might as well have a wad of chewing tobacco in your mouth," said Jack Henningfield, an associate professor of behavioral biology.
April 26, 2010 | By Melissa Healy, Los Angeles Times
A candy-like lozenge designed to satisfy a smoker's nicotine craving could prove dangerously tempting to little ones, researchers point out. Cinnamon- and mint-flavored Camel Orbs were launched on the U.S. market last year, aimed at smokers needing a nicotine fix when they can't light up. But the Tic Tac-sized product's "candy-like appearance and added flavorings" are virtually certain to tempt children to sneak one (or a few), with potentially disastrous effects, an article published in advance of May's issue of the journal Pediatrics concludes.
February 22, 2000 | From Times Wire Reports
New research suggests that nicotine may be useful in treating diseases that afflict the brain, including Alzheimer's, Parkinson's and Tourette's syndrome. Scientists experimenting with nicotine patches and synthetic nicotine described their studies at a Washington conference sponsored by the American Assn. for the Advancement of Science. They cautioned that smoking would not confer any benefit.
July 9, 2004 | From Reuters
A federal judge rejected a request by tobacco companies to have government allegations that they manipulated nicotine levels excluded from a landmark racketeering trial due to start Sept. 13. U.S. District Judge Gladys Kessler said nicotine manipulation was just one component of the government's allegations of an overarching fraud that deceived the public about the dangers of smoking and the addictiveness of nicotine.
November 1, 2002 | From Reuters
U.S. regulators approved a nicotine lozenge that will be sold in stores along with gums and patches to help people quit smoking. The over-the-counter Commit Lozenge provides smokers with a source of nicotine that helps them avoid cigarette cravings and withdrawal symptoms while they try to quit, maker GlaxoSmithKline said. London-based GlaxoSmithKline said the lozenges would be available in stores by the end of November.
April 29, 1999
French scientists have discovered how nicotine works in the brain to ease pain, which could pave the way for new drugs that are more effective but less addictive than painkillers such as morphine, they report in today's Nature. Nicotine, the addictive element in cigarettes, dulls pain by interacting with certain receptor molecules in the brain.
March 6, 1989 | From Times staff and wire service reports
Nicotine gum, chewed by smokers trying to kick the habit, is probably of little value in the way it is most often used, researchers said last week. The finding was based on a study of 315 smokers, some of whom were given the gum and others a look-alike without nicotine.
April 3, 2006 | From Times Wire Reports
Nicotine can prevent chemotherapy drugs such as Taxol from killing lung cancer cells, researchers reported in a finding that may help explain why lung cancer is so difficult to treat in smokers. The study was published by the Proceedings of the National Academy of Sciences. The researchers tested the drugs gemcitabine, cisplatin and Taxol on several cell lines taken from lung cancer tumors.
A key federal advisory panel declared Tuesday that nicotine is an addictive substance and concluded that the amounts of nicotine found in cigarettes now on the market could addict the "typical smoker," a finding expected to heavily influence an impending government decision to regulate cigarettes. The Food and Drug Administration's drug abuse advisory committee said that the addiction is caused by the pharmacologic, or drug-like, effects of nicotine.
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