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Osteoporosis

CALIFORNIA | LOCAL
October 3, 1996 | From Times staff and wire reports
Alendronate, a drug designed to build stronger bones in people prone to osteoporosis, can corrode the tube leading to the stomach if it is taken improperly, according to a study in the New England Journal of Medicine. A group led by Dr. Piet C. de Groen of the Mayo Clinic in Rochester, Minn., found three serious cases in which alendronate, trade named Fosamax, had apparently become lodged in the esophagus and had corroded its lining.
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CALIFORNIA | LOCAL
June 6, 1988 | From Times staff and wire reports
Younger women taking a commonly prescribed thyroid hormone may be at increased risk for bone-thinning osteoporosis if they are treated with too high a dose for a long period of time.
NEWS
November 4, 1987 | THOMAS H. MAUGH II, Times Science Writer
Boron, a trace element not previously known to be important in the human diet, may play a key role in preventing osteoporosis, a debilitating bone condition that afflicts many older women, U.S. scientists reported in a paper to be published today. If confirmed by additional human studies, the finding may have broad implications because osteoporosis, or the loss of calcium from the bone, affects up to 20 million mostly post-menopausal women in the United States alone.
CALIFORNIA | LOCAL
November 30, 1995 | From Times staff and wire reports
Even Bronze Age women had osteoporosis despite their presumably active lives, according to researchers from the Vienna University Hospital. The team reported in the New England Journal of Medicine that they used X-rays to determine the density of bones from 14 women buried at Unterhautzental, Austria, and found that they were about 11% less dense than bones from five men, indicating that the women were at greater risk for fractures.
BUSINESS
September 15, 1997 | From Bloomberg News
Merck & Co.'s osteoporosis drug, Fosamax, cuts the chances that patients with the bone-thinning disease will be hospitalized, according to findings released Sunday. Women treated with Fosamax, also called alendronate, were 20% less likely to be hospitalized than those taking a placebo, a study said. The study also provides the first evidence that older women who break a bone are more likely to be hospitalized for other reasons, Merck said.
BUSINESS
July 14, 1995 | From Associated Press
Americans may soon get their first new treatment for osteoporosis in 20 years. Government scientists declared Thursday that the drug Fosamax increases bone strength and reduces fractures in older women. An advisory committee unanimously recommended the Food and Drug Administration approve the drug, which would become the first non-hormonal treatment for the nation's 20 million osteoporosis patients.
HEALTH
May 9, 2005 | Linda Marsa, Special to The Times
Bone loss can be insidious, going unnoticed in millions of people -- most of them women -- until spinal damage becomes severe or until a hip fracture starts a spiraling physical decline. Drugs can fight the often-debilitating condition, known as osteoporosis, but they can cause unpleasant side effects. As a result, many people stop taking them, leaving their bones to become ever more brittle and more likely to break.
NEWS
May 19, 1998 | THOMAS H. MAUGH II, TIMES MEDICAL WRITER
A drug used to prevent osteoporosis in older women reduces the risk of breast cancer by as much as 70% without any serious side effects, researchers said Monday at a meeting of the American Society for Clinical Oncology in Los Angeles. The risk reduction produced by the drug, called raloxifene, is about the same as that reported earlier this year for tamoxifen, but the latter drug can increase the risk of endometrial cancer and blood clots.
HEALTH
November 9, 1998 | SHARI ROAN, TIMES HEALTH WRITER
The first guidelines advising doctors just who should undergo osteoporosis screening and how patients should be treated have been released by a consortium of nongovernment health organizations.
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