April 7, 1993 |
In a surprising discovery, UCLA researchers have found that atherosclerosis, better known as hardening of the arteries, may arise in part through the formation of bone in the arteries. The finding, reported today in the Journal of Clinical Investigation, could open the door to new therapies to prevent atherosclerosis, which is treated by controlling intake of cholesterol and fats, said Dr. Linda Demer, associate chief of cardiology at the UCLA School of Medicine.
CALIFORNIA | LOCAL
July 10, 1997 |
Medical scientists based at Childrens Hospital Los Angeles have shown that osteoporosis, a much-dreaded ailment of old age, appears to have roots in early childhood, with some children inheriting genes that increase their risk of brittle bones later in life. Led by Dr. Vicente Gilsanz, a radiologist at the hospital, and Jesus Sainz, a neurology researcher at the UCLA School of Medicine, the scientists used CT scanners to measure the bone density of 100 healthy girls between 6 and 12 years old.
July 23, 1987
The Southern California chapter of the Arthritis Foundation has awarded a $60,000 grant to UCLA endocrinologist Theodore Hahn for a study on rheumatoid arthritis and osteoporosis. Rheumatoid arthritis patients are at high risk at an early age for osteoporosis, a dangerous thinning of the bones, officials said.
July 26, 2008 |
Amgen Inc. said its experimental osteoporosis drug denosumab reduced fractures in women with the bone-thinning disease in a study. The trial of 7,800 women with osteoporosis found that denosumab strengthened bones and reduced spinal and hip fractures, the Thousand Oaks-based company said.
September 13, 2010 |
Dozens of drugs can weaken bones. Oral corticosteroids such as prednisone are especially problematic when used for long periods of time. Even inhaled steroids (Advair, Flovent, Symbicort, etc.) may pose problems over time. People with osteoporosis should work closely with a doctor to develop a treatment strategy. I have taken prednisone for years due to an arthritic condition. Because of stomach upset, my doctor has prescribed Nexium to prevent an ulcer. I was recently diagnosed with osteoporosis and wonder what can be done to counteract the bone-damaging effects of my medicine.
May 24, 1999
May is National Osteoporosis Month. Here are some facts about the disease, which is characterized by low bone mass and structural deterioration of bone tissue, which leads to bone fragility and an increased susceptibility to hip, spine and wrist fractures. * It's a major public health threat for an estimated 28 million Americans, 80% of whom are women. In the U.S., 10 million people have the disease and 18 million have low bone mass, putting them at risk for osteoporosis.
CALIFORNIA | LOCAL
August 31, 2000
Fosamax, a drug widely used to prevent brittle bones in women, can help strengthen men's bones as well, researchers report in today's New England Journal of Medicine. Dr. Eric Orwoll of the Oregon Health Sciences University and his team found that men who took the drug, whose generic name is alendronate, instead of a placebo had significant increases in the density of their spine and hip bones.