Patients

The Food and Drug Administration on Thursday cautioned consumers against using quinine for leg cramps, warning that the drug could cause severe side effects, including death. Quinine, sold in this country under the brand name Qualaquin, is approved for treatment of uncomplicated malaria, but has a long history of use as a remedy for leg cramps, especially at night. In many countries, it is sold over the counter. Studies have shown that it can reduce the incidence of cramps by one-third to one-half but that as many as one in every 25 users can suffer serious side effects.

What spreads almost as fast as necrotizing fasciitis, a.k.a. flesh-eating infection? News stories about it. Surely by now you've heard about the horrifying case of Aimee Copeland, the 24-year-old Georgia graduate student who cut her leg on May 1 and was on life support by May 4. When Copeland regained consciousness, much of the plugged-in world knew what she still did not: Her left leg had been amputated, skin on her abdomen had been removed and...

Until recently, very few people had ever heard of raspberry ketones, the aromatic compounds that give the berries their distinctive smell. Today, health food stores have trouble keeping the capsules or drops of the stuff on their shelves. Almost overnight, an obscure plant compound became the next big thing in weight loss - and all it took was a few words from Dr. Oz. In a February episode of "The Dr. Oz Show," Mehmet Oz told viewers that raspberry ketones were "the No. 1 miracle in a bottle to burn your fat. " Once Oz calls something a "miracle," it doesn't remain obscure for long.

Just before 10:45 a.m., Keith Marks called 911 and the Los Angeles County emergency response system sprang into action. A fire engine, a paramedic squad and a private ambulance - eight men in total - rushed to the Martin Luther King Jr. urgent-care center in Willowbrook. When they arrived, Marks, 56, was sitting calmly in a wheelchair just outside the entrance. His complaint: he was having joint pain from gout and wanted his medication refilled. "I can't walk," he said.

Asthma sufferers have long relied on inhalers for relief from wheezing or coughing attacks. But as of Dec. 31, Primatene Mist -- the only available over-the-counter asthma inhaler -- was taken off shelves because of its adverse effect on the environment. Other inhalers are available, but these require a doctor's prescription. Some people with asthma aren't happy about the change, but lung doctors and asthma specialists agree that Primatene Mist wasn't the best option for patients anyway.

Times are tough enough for Californians; they're even tougher for Californians' teeth. "One-quarter of all adults and 28% of children in California have untreated dental caries [cavities]," says Len Finocchio, a senior program officer at the California Healthcare Foundation, a health advocacy group. "Our research tells us that many people in California have been avoiding routine care that might have cost about $100 for a checkup and cleaning, and then find themselves in the emergency room, where they get only an antibiotic, a bill that can average over $600 and instructions to see a dentist."

Disco legend Donna Summer, 63, died Wednesday night, reportedly of lung cancer. As of press time, her family hadn't released details about her illness, so it was unknown what type of lung cancer she had, and how long she may have been ailing. According to the American Cancer Society , lung cancer is the leading cause of cancer death in both women and men, killing more than 150,000 people per year -- more than colon, breast, ovarian and prostate cancers combined. In 2012, the group estimates, there will be about 226,000 new cases of lung cancer in the U.S. Survival rates of people with lung cancer are low. Only about half of people diagnosed with early-stage non-small-cell lung cancer (the more common type)

Manny Hamelburg, 68, a retired businessman, had fought prostate cancer for years. First, he tried radiation, then a drug with side effects that nearly killed him, and finally Lupron, a drug that blocks production of testosterone, the hormone that can fuel prostate cancer. The cancer disappeared. But life was miserable. Without normal levels of testosterone, Hamelburg says, he had no energy, and "zero libido for seven years. I was like a eunuch. I was chemically castrated. Sex was just hugs."

The PSA test should be abandoned as a prostate cancer screening tool, a government advisory panel has concluded after determining that the side effects from needless biopsies and treatments hurt many more men than are potentially helped by early detection of cancers. At best, one life will be saved for every 1,000 men screened over a 10-year period, according to the U.S. Preventive Services Task Force. But 100 to 120 men will have suspicious results when there is no cancer, triggering biopsies that can carry complications such as pain, fever, bleeding, infection and hospitalization.

WASHINGTON - An experimental treatment for multiple sclerosis has caused death, strokes, nerve damage and abdominal bleeding and has no proven benefits for sufferers of the disease, the Food and Drug Administration warned Thursday. Known as liberation therapy, the treatment targets chronic cerebrospinal venous insufficiency - or CCSVI - a narrowing of the veins in the head and neck. It involves inserting balloons or stents into veins to widen them in an attempt to relieve the symptoms of MS. The FDA received reports in 2011 of a patient who died from bleeding in the brain after undergoing the treatment and another who was left permanently paralyzed by a stroke.

Diane Rodrigues sang, prayed and bounced on her bed during the night at Metropolitan State Hospital. A nurse assigned to keep her under constant watch sat by, occasionally dozing. By 7 a.m., the 52-year-old psychiatric patient was lying motionless on the floor, her neck broken. It took at least an hour for caregivers at the Norwalk mental hospital to glean the extent of her injuries. It took four more hours to send her to a trauma center for treatment. Rodrigues, a former kindergarten teacher, was left paralyzed after the November 2009 accident and died six months later from related respiratory complications.

It's tough enough to be without health insurance. But do healthcare providers have to make it even worse by treating you like a moron? Santa Monica resident Tom Wilde recently received bills from a downtown Los Angeles clinic and the L.A. County/USC Medical Center totaling almost $2,500. What exactly were the charges for? The bills didn't say. There was no itemizing of procedures and prices. No diagnosis. No treatment date. No nothing. Just a notation of "new charges" and the amount due. "They certainly wouldn't send such a bill to an insurance company," Wilde, 51, told me. "Insurance companies want to know exactly what they're paying for. " So you'd think.

State Sen. Ted Lieu (D-Torrance) is right to be offended by "conversion therapy," the pseudo-psychiatric treatment that purports to talk patients out of being gay and into being straight. There's no medical basis for the treatment, and there's some evidence that it causes harm while failing to do any good. As is so often the case, Lieu and his colleagues in the Legislature reacted to a perceived problem by proposing a bill. Lieu's legislation, SB 1172, which would make it illegal for California psychologists to attempt to convert gay minors, has passed the Senate Judiciary Committee and is working its way through the statehouse.

It sounds too good to be true, but a Chicago doctor is reporting that a drug-like dietary supplement, or nutriceutical, called Longevinex -- which contains the purported anti-aging chemical resveratrol -- may control or even reverse the symptoms of wet macular degeneration, a severe form of visual impairment. If the results prove to hold up, the treatment would have a great advantage over existing ones, which require injection of chemicals directly into the eye. Longevinex, in contrast, can be taken orally.

Just off the trendy Melrose strip, on the western edge of Hollywood, is a refuge of tree-lined streets where neighbors greet each other by name and young couples start families and stick around into their golden years. Lately, it has also become a battlefront in a broader clash of conflicting imperatives: how to balance a government push to keep the aging and disabled out of institutions against community desires to protect the character and value of residential neighborhoods, particularly in a shaky housing market.

Re "The testing glut," Opinion, May 2 Kudos to the medical specialty boards for recommending limits to unnecessary testing. A patient without symptoms who undergoes a routine exam will have at least 15 different blood tests done in addition to a number of radiological studies. These tests are usually negative, or they may be borderline and provoke further testing. Medical specialty boards are informing, but physicians must be receptive. Furthermore, patients should know that excessive testing is not good medicine.

A new study showing an estimated 7% of American teens and adults carry the human papillomavirus in their mouths may help health experts finally understand why rates of mouth and throat cancer have been climbing for nearly 25 years. The evidence makes it clear that oral sex practices play a key role in transmission. The new data, published online Thursday by the Journal of the American Medical Assn., are the first to assess the prevalence of oral HPV infection in the U.S. population.

What are the advantages and disadvantages of using the supplement nitric oxide? Richard Sunland Nitric oxide is a gas naturally found in the body; its function is conveying information between cells. One of its main jobs is increasing blood flow by dilating blood vessels, and that's why it's sometimes given in supplement form to heart patients, orally and intravenously. In at least one study it's been shown to be effective for lowering blood pressure.

State regulators determined that a Redding hospital owned by Prime Healthcare Services Inc. violated patient confidentiality by sharing a woman's medical files with journalists and sending an email about her treatment to 785 hospital workers. In a report issued this week, the California Department of Public Health found that Shasta Regional Medical Center had five deficiencies related to the unauthorized disclosure of medical information on a diabetes patient treated there in 2010.

Paging all Atul Gawande fans! Your favorite doctor-journalist is out with a new history on his own field: surgery. The article - part of a yearlong series celebrating the 200th anniversary of the New England Journal of Medicine - begins in 1812, when the newly established periodical is called the New England Journal of Medicine and Surgery, and the Collateral Branches of Science. The way surgery was practiced back then was not for the faint of heart. For starters, anesthesia would not be invented for another 34 years.