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Plos Medicine

SCIENCE
July 11, 2012 | By Erin Loury, Los Angeles Times
Treatment drugs can do more than improve the health of people with HIV: If administered early, medications can also reduce the spread of the disease to sexual partners and may help stem the AIDS epidemic. But many logistical hurdles stand in the way of making this strategy feasible, affordable and effective, according to experts writing in Tuesday's edition of the journal PLoS Medicine. The medications in question are antiretroviral therapies, which prevent HIV from multiplying and drastically diminish the amount of virus circulating in the blood.
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SCIENCE
July 30, 2013 | By Karen Kaplan, This post has been corrected, as indicated below.
Women, wouldn't you like to know your precise risk of developing breast cancer, ovarian cancer and endometrial cancer? And wouldn't you like to know what changes you could make in your life to reduce that risk? Researchers from the National Cancer Institute would like to help you. They've just published a study in the journal PLOS Medicine that takes a significant step toward that goal. Ruth Pfeiffer , a senior investigator in the National Cancer Institute's Division of Cancer Epidemiology and Genetics, and colleagues focused on the predictive value of more than a dozen variables, including a woman's body mass index , number of children she has, how long she took birth control pills, whether she used hormone therapy to treat symptoms of menopause, family history of gynecological cancers, and use of cigarettes and alcohol.
NEWS
November 8, 2011 | By Jeannine Stein, Los Angeles Times / For the Booster Shots blog
It will be an even 20 for Michelle and Jim Bob Duggar, who announced Tuesday that they're expecting their 20th child. The Duggars, stars of their own TLC show, are a source of fascination for some people, since super-sized families aren't the norm the way they were about a century ago. Michelle Duggar, you'll recall, didn't have such an easy time around with her last pregnancy in 2009. Daughter Josie was delivered early when it was discovered that Michelle had preeclampsia and gall bladder problems (Josie is now doing fine)
SCIENCE
November 26, 2013 | By Monte Morin, This post has been updated, as indicated below.
The 2009 H1N1 "swine flu" epidemic killed up to 203,000 people across the globe -- a death toll 10 times greater than initially estimated by the World Health Organization, researchers say. In a study published Tuesday in the journal Plos Medicine, epidemiologists used data on respiratory deaths in 20 nations to calculate a global mortality rate for the pandemic. Prior to this research, the WHO counted just 18,631 lab-confirmed cases of H1N1, a viral infection of the airways.
HEALTH
August 30, 2010 | By James S. Fell, Special to the Los Angeles Times
I don't have anything against cosmetic surgery. No amount of running or iron pumping was going to do anything about the genetically programmed dark circles under my eyes, so I got those things zapped with a nuclear-powered laser that made me twitch and fidget in the chair like a spider monkey coming off a meth bender. Cosmetic surgery can, quite simply, do things that diet and exercise can't. If you've got something that looks like that mutant from "Total Recall" hanging off your stomach telling you to "start the reactor," and it bothers you more than the sizeable surgery scars will, then getting some work done on this area could be an option.
SCIENCE
May 12, 2009 | Thomas H. Maugh II
Taking folic acid supplements for a year before conception reduces the risk of very premature birth by at least 50%, researchers reported Monday. Shorter courses of the supplement were not as effective, according to the study of nearly 35,000 women reported in the Public Library of Science journal PLoS Medicine. Folic acid's effectiveness in reducing the risk of neural-tube and other birth defects -- even without such a long course -- is long established.
WORLD
September 28, 2008 | Richard Boudreaux, Times Staff Writer
With $3 billion in new pledges, world leaders say they believe that an ambitious goal to stop deaths from malaria by 2015 is finally within reach. A plan billed as the most comprehensive ever to tackle the mosquito-borne disease, which kills nearly 1 million people each year, was unveiled last week at a United Nations gathering of heads of government, global health leaders and philanthropists.
SCIENCE
July 2, 2013 | By Melissa Healy
The twin plagues of economic hardship and low academic attainment turn out to be an inflammatory problem, not just for society but for the human bodies beset by them. And for many, including those in minority groups who disproportionately experience stunted economic and academic prospects, high rates of Type 2 diabetes are the common result, a new study says. The new research, based on a long-running study of British government workers, offers a partial explanation for a trend that is firmly established in industrialized democracies -- that where calories are plentifully available, those clinging to the lower rungs of the economic ladder are most likely to develop Type 2 diabetes.
NEWS
June 5, 2012 | By Karen Kaplan, Los Angeles Times/For the Booster Shots blog
Want to gauge your risk for developing Type 2 diabetes? Don't just step on the scale - reach for a measuring tape too, a new study suggests. The circumference of your waist can tell you a lot about your chances of getting diabetes, according to a study published Tuesday in the journal PLoS Medicine . Health providers usually rely on body mass index to determine patients' diabetes risk, but adding waist circumference to the equation would...
NEWS
January 5, 2011 | By Karen Kaplan, Los Angeles Times
Before embarking on a medically invasive, expensive and emotionally taxing effort to get pregnant through in vitro fertilization, it sure would be nice to get a good sense of whether it’s likely to work. After all, only about 1 in 4 attempts resulted in a live birth as recently as 2007. So researchers from England and Scotland scoured data from more than 144,000 IVF cycles in the United Kingdom and looked for factors that might predict which couples stood the best chance of having a baby with assisted reproduction and which faced long-shot odds.
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