February 17, 2011 |
The Food and Drug Administration on Thursday issued its strongest warning against the use of a drug prescribed off-label to prevent preterm labor, saying it appears to be ineffective at delaying premature births and poses serious health risks for pregnant woman who take it for longer than 72 hours. The warning comes less than two weeks after the FDA approved a new drug , called Makena, to reduce the risk of premature delivery. One in eight babies born in the U.S. each year -- 543,000 -- is born prematurely, says the March of Dimes . Terbutaline , commercially marketed as Brethine and Bricanyl, is a drug approved for the treatment of asthma and chronic obstructive pulmonary disorder, sometimes called emphysema.
February 4, 2011 |
For the first time, the Food and Drug Administration on Friday approved a drug to reduce the risk of premature delivery, although it required the manufacturer to conduct more studies to demonstrate the drug's efficacy. The agency gave the nod to a synthetic form of the hormone progesterone, which is normally produced during pregnancy, that can be injected into women who have already had a spontaneous preterm birth. The weekly injections, to be marketed under the name Makena, are for use only in women who are carrying a single fetus and who have no other risk factors for an early delivery.
May 11, 2010 |
For the first time in three decades, the rate of premature births in the United States has declined for two years in a row, a finding that suggests the country is finally beginning to make some progress in the battle against prematurity. The declines were widespread and encompassing, including babies of mothers in all age groups under 40, all ethnicities, singleton and multiple births, vaginal and caesarean births, and every state except Hawaii, according to the report issued Tuesday by the government's National Center for Health Statistics.
March 23, 2010 |
Aiming to cut down on the high number of premature births across the nation, a new program will offer words of advice for pregnant women in a place that will be hard to miss: on their cellphones. The free text messages will be sent every week and will include information about such things as seeing the doctor, avoiding alcohol and cigarettes, and eating properly. Although it's just rolling out, the program — called text4baby — already has more than 18,000 women signed up for what's expected to be the largest nationwide health initiative using mobile phones.
February 28, 2010 |
Bill and Marcia Stlaske's first pangs of fear coincided with her labor pains. Stlaske, 31, had given birth to two healthy sons, both delivered somewhat early. But their third, Tyler, was on the way nearly a month before his January due date. Doctors tried to stave off delivery but found Stlaske's amniotic fluid too low. "They said they had to take him early," said Marcia Stlaske, a second-grade teacher from Crystal Lake, Ill. "It was terrifying." Not long ago, Tyler's birth on Dec. 30 at 36 weeks' gestation would have been considered skirting the edge of prematurity, defined as being born before 37 weeks.
February 2, 2010 |
An infection of the uterine cavity during pregnancy combined with premature birth doubles the risk that an African American child will develop asthma, researchers have found. The combination also increases risk for some other ethnicities, though less severely. About 8% of pregnancies are marked by such bacterial infections, called chorioamnionitis, but it is not yet clear what proportion of asthma is induced by them, said the lead author, Dr. Darios Getahun of Kaiser Permanente's Department of Research and Evaluation in Pasadena.