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Retinoids

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BUSINESS
July 2, 1992 | JAMES M. GOMEZ, TIMES STAFF WRITER
Drip, drip, drip. The solution slowly fills the thin test tube under the watchful eye of Diana Colon, who sits placidly amid a jumble of laboratory equipment at Allergan Inc. The crystal-clear chemical, to be used in one of the company's dermatology products, is the result of months of work and is the latest of 400 synthetic "retinoids" to be distilled in the Irvine lab. "It's very exciting," said Colon, a 26-year-old chemist with a master's degree from UC Irvine.
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BUSINESS
December 11, 1993
Allergan Inc., an Irvine maker of skin and eye care products, and San Diego biotechnology firm Ligand Pharmaceuticals Inc. filed suit Friday against the La Jolla Cancer Research Foundation, accusing it of infringing on patented tests on a series of drugs used to treat skin ailments. The lawsuit, which did not claim specific damages, was filed in U.S. District Court in San Diego.
NEWS
April 7, 1998 | MARCIDA DODSON, TIMES STAFF WRITER
In a cluttered UC Irvine science laboratory about 2,000 miles from the bucolic lake where the alarming amphibians were first spotted, the mystery of the deformed Minnesota frogs may be close to being solved.
CALIFORNIA | LOCAL
April 5, 1998 | MARCIDA DODSON, TIMES STAFF WRITER
In a cluttered UC Irvine science laboratory some 2,000 miles from the bucolic lake where the alarming amphibians were first spotted, the mystery of the deformed Minnesota frogs may be close to being solved.
BUSINESS
July 23, 1998 | Bloomberg News
Allergan Inc. will receive as much as $104 million from Warner-Lambert Co. under an agreement to research and develop treatments for adult onset diabetes, the companies said Wednesday. The therapy will involve Allergan's developmental drugs based on retinoids, which are byproducts of Vitamin A, and Warner-Lambert's research into metabolic diseases.
BUSINESS
September 25, 1997 | Reuters
Allergan Inc. and Ligand Pharmaceuticals Inc. said they decided to dissolve their Allergan Ligand Retinoid Therapeutics Inc. joint venture, splitting the assets. The deal provides for a "clean, simple separation" of the company's assets, which are based on retinoid compounds, they said. Retinoids are agents that selectively regulate cell growth and are believed to have broad applications in treating cancer, skin disorders and other illnesses.
IMAGE
March 18, 2007 | Shari Roan, Times Staff Writer
SORTING through the confusing landscape of ointments, creams and solutions found at the cosmetics counter doesn't require an advanced degree. Common sense and a little product awareness go a long way. Read the label and the literature. Here's a list of what to look for. Retinoids and retinols: Retinoids are vitamin A derivatives that are available by prescription only, such as Retin-A and Renova. They're the only substances proven to soften fine lines and wrinkles.
NEWS
December 7, 2009 | Valerie Ulene, Los Angeles Times
More than 40 percent of teens have acne that's severe enough to require treatment by a physician, according to the American Academy of Dermatology. The first line of prescription medications include topical retinoids and antibiotics. Using these drugs in combination often produces the best results, but they must be taken for as long as the acne persists, which, for some people, can be many years. Although generally well-tolerated, they frequently cause skin dryness and irritation.
NEWS
August 29, 2011
Acnemedications and treatments fill drug store shelves, but some acne sufferers may have a tough time discerning which are the best to use. A paper published online in the journal the Lancet finds that certain studies on acne remedies are few and far between. In a seminar in the journal researchers from the U.S. and the U.K. reviewed the current slate of treatments available, including topical treatments such as benzoyl peroxide, retinoids and topical antibiotics, and oral treatments such as antibiotics, contraceptives and isotretinoin (the last typically used to treat severe cases of acne)
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