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ENTERTAINMENT
February 21, 2013
"Side Effects," Steven Soderbergh's tightly wound mind game, is definitely worth playing. It stars Jude Law as Dr. Banks, a psychiatrist counseling a suicidal young woman named Emily, played with great detachment by Rooney Mara. Emily gets only worse, until the doctor switches her meds. The upside, the depression lifts; the downside, Emily may have killed someone while sleepwalking, the result of a rare side effect. Soderbergh allows us to get as comfortable with the facts as Banks. Then he devilishly pulls the rug out from under us. It's fascinating to watch the doctor scramble to unspool what really happened.
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ENTERTAINMENT
April 24, 2014 | By John Horn
NEW YORK - As parents of young girls and as two of Hollywood's most prolific producers, Kathy Kennedy and Frank Marshall believed that "Columbine," journalist Dave Cullen's exhaustive investigation of the 1999 school massacre, contained compelling and often untold stories that needed to be shared with a larger audience. So when the book was published five years ago, the producers of "Lincoln" and "The Bourne Identity" purchased its rights, hoping to turn "Columbine" into a feature directed by "The Social Network's" David Fincher.
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ENTERTAINMENT
February 7, 2013 | By Amy Kaufman
“Identity Thief” will make a name for itself this weekend as the comedy is poised to easily pocket the No. 1 spot at the box office. The film, co-starring Melissa McCarthy and Jason Bateman, is set to debut with a strong $25 million, according to those who have seen pre-release audience surveys. The only other movie hitting theaters this weekend, Steven Soderbergh's psychological thriller “Side Effects,” will start off with a far lower sum of about $12 million. “Identity Thief” marks the first major feature film role for McCarthy, who gained massive popularity after her Oscar-nominated supporting turn in 2011's comedy “Bridesmaids.” Though she has appeared in a number of films over the years and stars in the CBS sitcom “Mike & Molly,” this year is the first that the 42-year-old actress will be able to prove she has box office clout.
ENTERTAINMENT
April 16, 2014 | By Christie D'Zurilla
Michael Douglas and Catherine Zeta-Jones reunited Tuesday night in New York, walking a red carpet in what was their first official public appearance as a couple since their split announcement last August.  Though the couple had reportedly been spotted together repeatedly in recent months, they took the occasion of the off-Broadway premiere of "The Library" at the Public Theater -- directed by Steven Soderbergh in his stage debut and starring Chloe...
SCIENCE
October 3, 2012 | By Jon Bardin
Nobody wants to be bitten by a black mamba. One of the most dangerous snakes in the world, its venom can kill a person in less than half an hour. But a new study reports that there is something besides deadly toxin hidden inside the snake: a powerful painkiller that works as well as  morphine but without the side effects. In the report, published Wednesday in the journal Nature, researchers from France described two previously unknown pain-killing peptides extracted from the mamba toxin.
ENTERTAINMENT
February 7, 2013 | By Kenneth Turan, Los Angeles Times Film Critic
Steven Soderbergh - who's indicated, not for the first time, that he's tired of filmmaking and may retire - has had a most unusual career. His persistent ennui has led him to all manner of narrative experiments, benighted projects like "Schizopolis" and "The Good German" that were doubtless more involving for him to make than for audiences to experience. But, as successes like "Erin Brockovich," "Out of Sight" and his new film, "Side Effects," demonstrate, when Soderbergh is willing to play it on the square, he's as good as anyone at bringing intelligence and verve to straight-ahead material.
HEALTH
November 8, 2004 | Elena Conis
The impressive pau d'arco tree of the Central and South American rain forests grows to well over 100 feet tall, with a trunk that can reach 6 feet wide. Known by the scientific names Tabebuia avellanedae and Tabebuia impetiginosa, it was named pau d'arco, or bow stick, by Portuguese colonists centuries ago in Brazil. The Inca used the bark to make healing tonics, and natives of the Brazilian rainforest have used the hardwood to make boats and weapons.
SCIENCE
March 18, 2013 | By Amina Khan
Sizzurp, purple drank, lean -- that cough-syrup-laced concoction of many  names -- has been gaining popularity in hip hop culture and notoriety as more celebrities fall prey to its effects. Rapper Lil Wayne was hospitalized at Cedars-Sinai last week, reportedly linked to use of the prescription-strength medication. The codeine in the medicine serves as a pain reliever and also suppresses coughing, said Dr. George Fallieras, an emergency room physician and hospitalist at Good Samaritan Hospital.
NEWS
January 24, 2011 | By Shari Roan, Los Angeles Times
Antidepressants can help people recovery from major depression, but some people dislike the medications because of their effects on sexual function. An antidepressant approved by the Food and Drug Administration on Monday, however, appears to have fewer sexual side effects. The drug, called Viibryd (or vilazodone), is the first antidepressant that is a selective serotonin reuptake inhibitor combined with and a 5HT1A receptor partial agonist. Many of the so-called SSRI antidepressants, such as Prozac or Zoloft, work on the serotonin system of the brain.
ENTERTAINMENT
February 11, 2013 | By Steven Zeitchik
The current state of our healthcare system, and especially the pervasiveness of prescription pills, have been the subject of great and compelling interest to news outlets over the last few years. But it's not exactly been the stuff of great multiplex excitement. We received more proof this weekend with the opening of “Side Effects” . The movie, which tells of a troubled woman (Rooney Mara) for whom things begin to go askew when she tries a new psychiatric medication, grossed a dismal $10 million in U.S. theaters despite the presence of popular stars (Channing Tatum plays Mara's husband)
ENTERTAINMENT
April 16, 2014 | By David Ng
Steven Soderbergh made his New York debut as a stage director on Tuesday with the official opening of "The Library," a school-shooting drama starring Chloe Grace Moretz, at the Public Theater in New York. Penned by frequent Soderbergh collaborator Scott Z. Burns, "The Library" had been in previews since March 25. The play is scheduled to run at the Public through April 27. Moretz plays a student who survives a deadly shooting at her high school and then struggles to tell her story to her parents and the authorities.
HOME & GARDEN
February 14, 2014 | By Jim Cox
I have to make sure when I get hold of happiness to seize the moment and soar to heights with it. I am grateful that I can still be joyful at times with simple and new things that were not significant to me before. - Bien Cox, journal entry The "new normal" arrived April 9, 2008. The painful lump in Bien's left breast was malignant. Cancer. The phone, the unholy messenger, was put back in its cradle, and we sat on the couch for a few moments. Tears came and went. Disbelief remained.
ENTERTAINMENT
January 16, 2014 | By David Ng
For someone who has retired from his main gig of directing movies, Steven Soderbergh has been keeping a busy schedule. In addition to working on the new cable mini-series "The Knick" and publishing a novel in tweet form, Soderbergh will direct a new play starring Chloe Grace Moretz that will open at New York's Public Theater in April. "The Library," penned by frequent Soderbergh collaborator Scott Z. Burns, will start performances at the Public on March 25 and will have an official opening on April 15. The world premiere at the Public is scheduled to run through April 27. Moretz will play a student who survives a deadly shooting at her high school and then struggles to tell her story to her parents and the authorities.
SCIENCE
November 20, 2013 | By Karen Kaplan
Could PTSD be partly responsible for the nation's obesity crisis? It's an intriguing question, considering that one out of every nine women will meet the diagnostic criteria for posttraumatic stress disorder at some point in their lives. People with PTSD are known to eat and drink things that aren't good for them and to blow off chances to exercise.  PTSD and depression are often fellow travelers, and depression can lead to weight gain. PTSD is also thought to be a risk factor for cardiometabolic diseases.
SCIENCE
November 13, 2013 | By Melissa Healy, This post has been corrected. See note below.
Less than five months after a pair of biotech companies submitted a candidate cancer drug to the Food & Drug Administration, the FDA has approved the drug ibrutinib as a "breakthrough therapy" for a rare and deadly form of the cancer, mantle cell lymphoma. The new medication, to be marketed under the commercial name Imbruvica, becomes a new option for patients who are diagnosed with this malignancy of the immune system's B-cells and who have received at least one prior therapy. The medication is the first product developed by Sunnyvale, Calif., biotech firm Pharmacyclics, where its promise as a treatment for B-cell malignancies such as lymphoma became evident in 2009.
SCIENCE
November 12, 2013 | By Melissa Healy
Dramatically escalating the fight against heart attacks and strokes, the nation's cardiologists have rewritten the guidebook on how Americans should be treated with statins and unveiled a plan that could double the number of patients taking the cholesterol-lowering drugs to about 70 million. The new approach, presented Tuesday by the American College of Cardiology and the American Heart Assn., represents a stark shift from the way doctors have prescribed the popular drugs for most of the last decade.
HEALTH
August 9, 2010 | By Devon Schuyler, Special to the Los Angeles Times
Statins are widely considered to be one of the safest drugs available. An estimated 24 million Americans take the cholesterol-lowering drugs, and most of them feel no different after their daily dose. "The vast majority of patients tolerate statins extremely well," said Dr. Gregg C. Fonarow, a professor of cardiovascular medicine at UCLA. But like any drug, statins carry a risk of side effects. With so many people taking them, and millions of other potential users out there, doctors and patients need to be alert for symptoms that could be related to the drugs.
ENTERTAINMENT
April 23, 2013 | By Gerrick D. Kennedy, Los Angeles Times
Fantasia was ready to walk away from her music, and her life, not so long ago. "I was starting to hate what I loved - the label, the industry," said the R&B singer on the eve of her first album in nearly three years, "Side Effects of You. " "I was at a place where I knew what I wanted. And if I couldn't have it, I didn't want to do it anymore. " Fantasia Barrino was only 20 when she won the third season of "American Idol" in 2004. She then made a successful record, released a memoir, starred in a Lifetime movie about her own life and even tackled Broadway.
OPINION
September 25, 2013
Re "What's this global warming 'hiatus'?," Sept. 23 I'm not a climate scientist and will not attempt to argue the interpretation of the data presented in this piece, but I do know what the word "hiatus" means: merely a lapse in continuity - in this case, with the extent of global warming predictions. This is by no means an excuse to continue burning fossil fuels in lieu of using clean, renewable energy sources. If my doctor told me to stop smoking or I'd be dead by age 50, and I ended up turning 51, does that prove he's wrong and I should continue smoking?
CALIFORNIA | LOCAL
August 2, 2013 | Alan Zarembo
Federal drug officials have issued a strong new warning about a controversial anti-malaria medication once routinely given to U.S. troops, some of whom say it damaged them permanently. The Food and Drug Administration ordered manufacturers of mefloquine hydrochloride to give the medicine a black box label, the agency's strongest warning, reserved for drugs with significant risks of serious side effects. The FDA said that some neurological and psychiatric side effects can last for months or years after a patient stops taking the drug.
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