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Statins

NEWS
November 14, 2001 | THOMAS H. MAUGH II, TIMES MEDICAL WRITER
Cholesterol-lowering drugs called statins can dramatically reduce the risk of heart attacks and strokes in patients with heart disease, even if their cholesterol levels already are normal, according to the largest study of the drugs ever conducted. The research, performed at Oxford University in England, could lead to a major shift in the treatment of heart disease--reducing death rates and the need for surgery.
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HEALTH
January 22, 2011 | By Amanda Leigh Mascarelli, Special to the Los Angeles Times
When it comes to cholesterol, doctors are sure of two things: High levels of the bad kind increase the risk of heart disease, and lowering those levels reduces the risk. So traditional treatments are aimed at cutting bad cholesterol through diet, exercise and drugs called statins. Now cardiologists are trying to harness the power of good cholesterol to help stave off heart disease. Clinical trials of drugs designed to boost good cholesterol are underway. Meanwhile, scientists are learning more about how it contributes to health: A new study suggests it's not just the total amount of good cholesterol that matters, but how efficiently it's able to gobble up bad cholesterol.
HEALTH
February 27, 2006 | Marc Siegel, Special to The Times
She was in good health, rode horses regularly and, as an articulate attorney, was not one to simply accept my medical advice without explanation. She came in for yearly checkups, and we had developed a good rapport during the last 10 years. Our main discussion concerned her cholesterol level: It generally ranged between 230 and 260, with a "bad" cholesterol (low-density lipoprotein) measurement of between 140 and 160.
HEALTH
November 6, 2006 | From Times wire reports
A device that helps severely damaged hearts pump may be able to do what was once thought impossible -- reverse heart failure in people who are weeks from death. The left ventricular assist device, or LVAD, can boost the heart's ability to function, allowing it to recover if used with the right drugs, British researchers have found. The team used the device and a combination of heart drugs in 15 patients who had severe heart failure.
HEALTH
June 22, 2009 | Joe Graedon and Teresa Graedon
In less than two years on Lipitor, I went from being able to climb the ancient temples at Angkor Wat, Cambodia, to being almost unable to walk to my mailbox. I felt like I had the flu all the time. I had pains in my fingers, arms, shoulders, hips, legs and feet. My doctor took me off Lipitor. Four days later, I could move my fingers again. Many readers report that muscle pain can be a side effect of statin-type medications. There may be a genetic basis to this.
HEALTH
July 23, 2007 | Joe Graedon and Teresa Graedon, and and Special to The Times
I have tried many statin drugs for cholesterol, but all gave me muscle pain and cramps. My doctor put me on Zetia and insists it can't cause muscle pain since it is not absorbed into the bloodstream. I still have muscle pain, cramps and tingling in my legs and feet. Can Zetia cause this? Although Zetia works differently from statin cholesterol-lowering drugs such as Lipitor or Zocor, it is absorbed into the bloodstream.
HEALTH
January 14, 2008 | Chris Woolston, Special to The Times
Could you review red yeast rice? I've started taking it in an attempt to lower my cholesterol and stay off statins. Diana Sherman Oaks The products: Lowly fungi have an amazing ability to create compounds that have strong effects on humans (alcohol, hallucinogens and antibiotics, to name a few). As far back as the Tang dynasty in 800, the Chinese harvested a red extract produced by certain types of fungi growing on rice.
OPINION
November 22, 2013
Re "A second opinion on statins," Editorial, Nov. 19 When it comes to reducing heart attacks, decreasing inflammation in blood vessels trumps reducing cholesterol. Diet and exercise can be just as effective as statins in this area, but many dismiss these efforts. Maybe that's because most of the unimpressive research used a high-carb, low-fat diet. Individuals at risk for heart disease are often insulin resistant. Of course the high-carb approach was ineffective. Second, dietitians and other qualified nutritionists should be reimbursed by Medicare and other insurance plans for doing what they do best.
NEWS
May 27, 2011 | By Marissa Cevallos, HealthKey / For the Booster Shots blog
Small studies had hinted that large doses of niacin might help prevent heart attack or stroke, and hopes were high that this might prove to be the case. Now those hopes appear dashed. The NIH has stopped a trial 18 months ahead of schedule after finding that combining extended-release, high-dose niacin with a statin doesn't seem to reduce the risk of such cardiovascular events. Niacin, or vitamin B3, is often taken to help reduce blood levels of triglycerides and LDL, the so-called bad cholesterol, and to boost levels of HDL, the so-called good cholesterol.
HEALTH
December 22, 2008 | By Erin Cline Davis, Los Angeles Times Staff Writer
Should statin drugs be put in the water, or what? More than 13 million Americans are taking these medications to lower their cholesterol and hopefully stave off heart disease -- a job the drugs appear to excel at. Statins can lower "bad" LDL cholesterol by 20% to 60%. Over time, this can lower the risk of having a heart attack by about the same amount. For many years, it was believed that statins worked solely by reducing blood cholesterol, which can build up in sticky plaques in the arteries that supply blood to the heart, potentially blocking blood flow and causing heart attacks.
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