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Stem Cell

August 26, 2010
A glimmer of hope among those with Alzheimer's, Parkinson's, diabetes and other ailments that might be relieved with new treatments derived from embryonic stem cells was dimmed this week by a federal judge, whose injunction on federal funding for such research could not only jeopardize American medical science but the health of millions of patients worldwide. But the failure isn't just judicial — the ruling was based in part on a sound interpretation of an ill-considered law imposed by Congress.
April 17, 2014 | By Monte Morin
Scientists have replicated one of the most significant accomplishments in stem cell research by creating human embryos that were clones of two men. The lab-engineered embryos were harvested within days and used to create lines of infinitely reproducing embryonic stem cells, which are capable of growing into any type of human tissue. The work, reported Thursday in the journal Cell Stem Cell, comes 11 months after researchers in Oregon said they had produced the world's first human embryo clones and used them to make stem cells.
March 10, 2009 | Karen Kaplan
With the stroke of a pen, President Obama cleared the way Monday for the National Institutes of Health and other federal agencies to fund research using all kinds of human embryonic stem cells. "Scientists believe these tiny cells may have the potential to help us understand, and possibly cure, some of our most devastating diseases and conditions," Obama said at the signing ceremony. Obama's executive order removes funding restrictions put in place by President George W.
April 9, 2014 | By Karen Kaplan
The Japanese stem cell scientist who was accused of misconduct by her own research institution apologized Wednesday for making careless mistakes but insisted that her STAP stem cells are real. Haruko Obokata told reporters at a news conference that she “produced the STAP cells successfully more than 200 times, and this is the truth,” according to the Yomiuri Shimbun's Japan News . The cells -- known formally as stimulus-triggered acquisition of pluripotency cells -- were described in a pair of studies published in January in the journal Nature.
January 21, 2012 | By Michael Hiltzik
  What are the chances that the prestigious Institute of Medicine will get an objective and balanced view of California's stem-cell program when it takes public testimony about the program at a hearing Tuesday in San Francisco? About 418 million to one. That's the estimation of the California Stem Cell Report. The report's proprietor, David Jensen, toted up the value of the grants received from the program by Tuesday's witnesses or their employers. Total: $418 million.
November 12, 2010 | By Shari Roan, Los Angeles Times
A specific type of stem cells transplanted into the leg muscles of injured young mice not only repaired the muscle damage but triggered changes in the muscle tissue that made it resistant to normal aging. The surprising finding, which was published Wednesday in Science Translational Medicine suggests that, under the proper conditions, stem cells might regenerate muscle tissue. Researchers led by Bradley Olwin of the University of Colorado, Boulder, took stem cells from the muscles of young donor mice and transplanted them into mice with muscle injuries.
March 7, 2009 | Karen Kaplan and Noam N. Levey
Making good on a popular campaign pledge, President Obama will sign an executive order Monday rescinding restrictions on federal funding for human embryonic stem cell research, administration officials said Friday -- instantly making hundreds of millions of new dollars available for the controversial science.
July 24, 2013 | By Eryn Brown
The governing board of the California Institute for Regenerative Medicine , or CIRM, will vote Thursday on whether to move ahead with a five-year, $70-million plan to establish a network of stem cell clinics. According to a proposal posted on CIRM's website , the CIRM Alpha Stem Cell Clinics Network will be composed of up to five clinics in California, each affiliated with an established research institution and all designed to make it easier for researchers to conduct -- and for patients to find -- clinical trials of stem cell therapies.
January 24, 2009 | Karen Kaplan
Ushering in a new era in medicine, the U.S. Food and Drug Administration said Friday that it had cleared the way for the world's first clinical trial of a therapy derived from human embryonic stem cells. By early summer, a handful of patients with severe spinal cord injuries will be eligible for injections of specialized nerve cells designed to enable electrical signals to travel between the brain and the rest of the body.
August 24, 2006
SCIENCE TOOK AN UNNECESSARY leap forward Wednesday. A Bay Area biotechnology company announced a breakthrough in stem cell research that could quell religious objections to such research and persuade the federal government to lift its restrictions on funding it.
April 1, 2014 | By Monte Morin
Research that made international headlines with a purported breakthrough in the creation of highly valuable stem cells has been found to contain falsified and manipulated data, according to a panel of Japanese investigators. At a news conference in Tokyo on Tuesday, the government's RIKEN research institute announced that it had concluded an investigation into allegations of misconduct, and found that the lead author of the study had improperly altered images of DNA fragments used in the research.
March 27, 2014 | Monte Morin
As new revelations further discredit a highly publicized Japanese study on the use of acid to create so-called STAP stem cells, scientists in the U.S. have quietly announced a research breakthrough that involves a more traditional means of producing the amazingly versatile cells. In a paper published Wednesday in the journal Nature, researchers said they had successfully generated embryonic stem cells using fertilized mouse embryos -- a feat that many scientists had thought was impossible.
March 14, 2014 | By Karen Kaplan and Monte Morin
The Japanese research institution at the center of a growing controversy over a new type of stem cells said Friday that its investigation of four scientists has confirmed two instances of "inappropriate" behavior but that neither case was severe enough to be considered intentional misconduct or outright fabrication of data. An investigative committee at RIKEN, which is funded primarily by the Japanese government, has been looking into charges that two high-profile papers published in January in the journal Nature included plagiarized material, duplicate photos and doctored figures.
March 11, 2014 | Karen Kaplan
A number of scientists have been grumbling for weeks about a pair of breakthrough stem cell studies that seemed too good to be true. Now one of the senior researchers who worked on the papers agrees that they may be right. The studies, which were published in January by the journal Nature, described a surprisingly simple method of transforming mature cells into pluripotent stem cells capable of regenerating any type of tissue in the body. The key was to stress them out by soaking them in an acid bath for 30 minutes, prompting genetic changes that made the cells more flexible.
January 29, 2014 | By Monte Morin
In a feat that experts say is a significant advance for regenerative medicine, scientists have discovered a surprisingly simple method for creating personalized stem cells that doesn't involve human embryos or tinkering with DNA. Two studies published Wednesday in the journal Nature describe a novel procedure for “reprogramming” the blood cells of newborn mice by soaking the cells in a mildly acidic solution for 30 minutes. This near-fatal shock caused the cells to become pluripotent, or capable of growing into any type of cell in the body.
November 4, 2013 | By Larry Gordon
Thanks to a $100-million donation, UC San Diego will be creating a new clinical center to study how the use of stem cells may help cure or alleviate leukemia, spinal cord injuries, Alzheimer's disease and other health problems, officials announced Monday. The gift is from  T. Denny Sanford , a South Dakota businessman who made a fortune in the banking and credit card industry and has been very generous to various healthcare initiatives. The new Sanford Stem Cell Clinical Center at UC San Diego will integrate researchers affiliated with the UC medical center there and several other nearby organizations in the La Jolla area, including the Salk Institute for Biological Studies, the Scripps Research Institute and the Sanford-Burnham Medical Research Institute.
October 24, 2005
IF SCIENCE COULD CREATE embryonic stem cells without harming embryos, then just about everyone would be happy. Those who believe that life begins at conception would have no objection. The federal government would be able to fund promising research instead of limiting scientists to existing cell lines that are mostly tainted. And U.S. scientists could compete on an equal basis with others around the world.
September 11, 2013 | By Eryn Brown
Researchers have reprogrammed cells inside living mice -- and have discovered that the pluripotent stem cells created in the process are even more flexible than those derived from embryos or grown in laboratory dishes. Someday the achievement might help scientists devise ways to treat human disease by directly regenerating tissues within human patients, said Manuel Serrano, an investigator at the Spanish National Cancer Research Center in Madrid and senior author of a study ( abstract here )
August 5, 2013 | By Ricardo Lopez
For a $330,000 burger, taste testers thought the flavor fell a little flat.  The hefty price tag, however, wasn't for some fancy, rare cut of meat. In fact, this meat had never so much as mooed in a previous life: It was beef grown in a laboratory.  Dutch scientists Monday unveiled their ambitious research project, years in the making, with a public taste test of their cultured beef in London.  Volunteer tasters sampled hamburger made from the lab-grown beef made from stem cells.
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