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Stem Cells

SCIENCE
July 24, 2013 | By Eryn Brown
The governing board of the California Institute for Regenerative Medicine , or CIRM, will vote Thursday on whether to move ahead with a five-year, $70-million plan to establish a network of stem cell clinics. According to a proposal posted on CIRM's website , the CIRM Alpha Stem Cell Clinics Network will be composed of up to five clinics in California, each affiliated with an established research institution and all designed to make it easier for researchers to conduct -- and for patients to find -- clinical trials of stem cell therapies.
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SCIENCE
July 3, 2013 | By Karen Kaplan
Scientists trying to use stem cells to grow organs in the lab have been going about it the wrong way, Japanese researchers say. Instead of trying to make a fully functional organ to transplant into a patient, they should create an immature version and let it grow inside the patient's body. The researchers, from Yokohama City University, showed that their approach can make a human liver that performs essential liver tasks when placed inside a mouse. They described their experiments in a study published Wednesday by the journal Nature.
OPINION
May 29, 2013 | Patt Morrison
In 2004, with President George W. Bush dead set against stem cell research, California just went ahead and did it. Voters made stem cell research a state constitutional right, and endorsed $3 billion in bond sales for 10 years to cement the deal. CIRM, the California Institute for Regenerative Medicine created under Proposition 71, has become a world center for stem cell research, and its president is Australian Alan Trounson, a pioneer in in vitro fertilization. As Proposition 71 approaches its 10-year anniversary, Trounson offers a prognosis.
OPINION
May 19, 2013
Re "Stem cells are made by cloning method," May 16 Cloning a human serves no purpose, so the arguments against making stem cells using a cloning method are ludicrous. On the other hand, cloning organs makes sense - the rest is just jibber-jabber from Luddites. Mike Benbrook El Cajon ALSO: Letters: Dying but not wanting to know Letters: Addiction treatment that works Letters: Election billboard ads may backfire
OPINION
May 17, 2013 | By The Times editorial board
A breakthrough in stem cell research has again raised the specter of human cloning. The discovery by a team at Oregon Health and Science University moves the world incrementally closer to that result, but its more immediate effect will be to spur efforts to regenerate healthy tissue for the injured and the ailing. Although it's reasonable to worry about where such a discovery may lead, those concerns shouldn't stop researchers from exploring the restorative properties of stem cells. The promise of stem cells is that they can develop into many different kinds of tissues rather than being locked into a specific cellular fate.
SCIENCE
May 15, 2013 | By Melissa Healy, Los Angeles Times
For the first time, scientists have created human embryos that are genetic copies of living people and used them to make stem cells - a feat that paves the way for treating a range of diseases with personalized body tissues but also ignites fears of human cloning. If replicated in other labs, the methods detailed Wednesday in the journal Cell would allow researchers to fashion human embryonic stem cells that are custom-made for patients with Alzheimer's disease, diabetes and other health problems.
SCIENCE
April 13, 2013 | Eryn Brown and Joseph Serna
Clive Svendsen doesn't get rattled easily, but the neurobiologist couldn't help sweating when Stephen Hawking paid a visit to his lab this week. Hawking is one of the world's foremost theoretical physicists. He pioneered groundbreaking research into how particles behave around black holes and deduced that black holes spit out radiation as they swallow up matter. He's also credited with teaching millions about the mysteries of the cosmos through his books, including the bestseller "A Brief History of Time.
OPINION
February 27, 2013
After years of resisting all criticisms of its operations, the California Institute for Regenerative Medicine is finally listening - a little. It spent $700,000 for an outside, high-level review that complimented the stem cell agency for funding an excellent portfolio of research projects, but also raised serious objections to the agency's structure, which the review said was likely to lead to financial conflicts of interest. The criticisms were nothing new - many of the same points have been made since the agency was created by Proposition 71 in 2004 - but the positive response by the chairman of the agency's board was. The governing board is now making changes to address some of the long-standing issues.
BUSINESS
January 29, 2013 | Michael Hiltzik
Compromise, defined as the art of getting part of a loaf when the whole loaf is out of reach, comes in many forms. But surely the strangest of all is what comes of trying to compromise with yourself. That's what California's stem cell agency is attempting to do. And judging from its record of pioneering new ways of funding and managing scientific research, you can rest assured that the results will be fraught with interest. What's at issue is how the agency's board wrestles with recommendations for changes in its membership and its authority over the spending of its $3-billion endowment in state bond funds (that's $6 billion, including interest)
NEWS
January 25, 2013 | By Eryn Brown
Changes may be on the way at California's stem cell funding agency.  The California Institute for Regenerative Medicine, or CIRM, came under fire in December when an Institute of Medicine report concluded that the agency was plagued by conflicts of interest. (See story in related items at left.)   In response, CIRM's governing board on Wednesday endorsed a “framework” designed to address some of those concerns. Chief among the changes: Board members from universities and other research institutions who compete for CIRM funding would no longer vote on grants.
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