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CALIFORNIA | LOCAL
January 4, 2009 | Richard Marosi
Smuggler's Gulch lived up to its infamous name. For a century, the narrow canyon leading into California from Mexico provided cover for cattle thieves and opium dealers, bandits and booze runners. More recently, it has hidden thousands of illegal immigrants on their journey north, sealing its place in border lore. Now, it's a fading memory.
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ENTERTAINMENT
December 16, 2008 | Richard Rushfield, Rushfield is a Times staff writer.
With the debut of Season 8 a mere 28 days away, "American Idol" producers are offering the first hints of what looks to be the biggest shake-up in its format since the show's early seasons. In an exclusive conversation, executive producer Ken Warwick confirmed the rumors sweeping the Internet on some of the changes afoot, knocked down a few others, urged patience on some more and gave his thoughts and insight on the entire shake-up. Below are a few high points: Warwick said the biggest challenge to making this season work stems from the show having been on the air for so long.
BUSINESS
November 15, 2008 | bloomberg news
Some people who received injections of dermal wrinkle fillers suffered "serious and unexpected" side effects, such as the loss of control facial muscles, disfigurement and rare life-threatening allergic reactions, U.S. regulators said Friday. There were 930 reports of side effects of all types from January 2003 to Sept. 20 of this year for products made by various companies, according to a Food and Drug Administration staff review. The reports came from the U.S. and elsewhere.
BUSINESS
October 10, 2008 | From Times Wire Services
The safety of skin wrinkle fillers from companies led by Medicis Pharmaceutical Corp. and Allergan Inc. will be reviewed by a U.S. advisory panel next month. Food and Drug Administration advisors will meet Nov. 18 in Gaithersburg, Md., to hear safety concerns and recommend studies for existing and new wrinkle treatments, according to a notice posted on the agency's website. The next day, the advisory panel will discuss evaluation of cosmetic devices that use various energy sources to treat skin conditions.
BUSINESS
September 12, 2008 | From the Associated Press
Botox, the botulism-based drug that has wiped wrinkles from the faces of millions, may be approved for another use: stopping headaches. Drug maker Allergan Inc. said Thursday that it had new evidence that its injectable drug could help relieve migraine headaches. Based on preliminary results from two company-funded studies, Allergan said it would ask the Food and Drug Administration to approve Botox for chronic migraine next year. The FDA approved Botox to smooth wrinkles and age lines in 2002, and it has grown into a blockbuster product for Irvine-based Allergan, with $2.1 billion in sales last year.
BUSINESS
July 10, 2008 | Lisa Girion, Times Staff Writer
More than a dozen Botox users and relatives filed a lawsuit Wednesday contending that the blockbuster wrinkle-buster injured them or killed their relatives, and they blamed maker Allergan Inc. for failing to warn them of the dangers. The suit, filed in Orange County Superior Court near Allergan's Irvine headquarters, links the toxin-based drug to three deaths, including one in March of a 69-year-old Texas nurse who received injections for neck and shoulder pain.
BUSINESS
July 1, 2008 | From Times Wire Services
Johnson & Johnson won U.S. approval for Evolence, an injectable wrinkle filler that will compete in a market forecast to grow to more than $847 million by 2012. The Food and Drug Administration cleared the collagen-based filler for "correction of moderate to deep facial wrinkles and folds," J&J said. The drug was approved in Europe in 2004. Evolence uses collagen from pigs.
ENTERTAINMENT
June 23, 2008 | August Brown, Times Staff Writer
The Los Angeles hard-core quintet the Bronx had an interesting take on the potential of punk rock during the Vans Warped Tour's kickoff show Friday at the Pomona Fairplex. "There is no revolution," howled singer Matt Caughthran during the track "Heart Attack American" in a ferocious early afternoon set. The Vans Warped Tour, the longest-running traveling music fest going today, has never really been about bona fide upheaval -- see the corporate sponsorship in the festival's title.
HOME & GARDEN
May 1, 2008 | Janet Eastman, Times Staff Writer
THE MOSAIC on the ceiling looks as old as the 1921 house. Actually, older. Griffins guard one side, twin phoenixes another. Grapevines coil across a trellis. The motifs are ancient. But the artwork? Completed last month. It took a house painter from Sierra Madre to propose the idea. The son of one of Mexico's most prominent muralists to guide the execution. A researcher at the Boston Public Library to keep it historically accurate.
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