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The PSA test should be abandoned as a prostate cancer screening tool, a government advisory panel has concluded after determining that the side effects from needless biopsies and treatments hurt many more men than are potentially helped by early detection of cancers. At best, one life will be saved for every 1,000 men screened over a 10-year period, according to the U.S. Preventive Services Task Force. But 100 to 120 men will have suspicious results when there is no cancer, triggering biopsies that can carry complications such as pain, fever, bleeding, infection and hospitalization.

A scathing review of the new stage musical "An Officer and a Gentleman" has prompted the show's writer to hit back in an editorial that recently ran in the Australian press. Douglas Day Stewart co-wrote the book for the musical, which based on his original screenplay for the 1982 movie starring Richard Gere and Debra Winger. "Officer" opened earlier this month at the Lyric Theatre in Sydney, Australia.

The alarm over potential bank runs in Greece and Spain this week has highlighted an often-overlooked fact: Europe's debt crisis is also, in many ways, a major banking crisis. In capitals such as Athens, Madrid and Rome, large portions of the sovereign debt racked up by spendthrift governments are owed to the countries' own banks, locking governments and the banks in an embrace so tight that disaster for one would almost certainly spell doom for the other. International bailouts for Greece, Ireland and Portugal have helped to keep not just their governments but also their banks afloat, as well as financial institutions in other parts of Europe with large exposure to those nations' debts.

Are You My Mother? A Comic Drama Alison Bechdel Houghton Mifflin Harcourt: 290 pp., $22 First things first: If you haven't read "Fun Home," Alison Bechdel's 2006 family memoir in comic form, drop everything and get a copy right away. In its pages, Bechdel does the miraculous: tracing deftly and with nuance her complex, claustrophobic relationship with her father, an English teacher and closeted gay man who died in 1980 (in what was either accident or suicide), shortly after Bechdel came out as a lesbian.

"Oh, you mean the guy with the 70-year-old head and the 20-year-old body-builder body? That picture has got to be Photoshopped." Dr. Jeffry Life smiles when I tell him about the general reaction I get about the famous picture of him with his shirt off, the shot that turned a mild-mannered doctor in his mid-60s into a poster boy for super-fit aging and controversial hormone replacement Appearing in medical-clinic ads in airline magazines and...

Rats fed fructose-laced drinking water for six weeks performed more slowly in a maze-navigating task, UCLA researchers have found. (Read this L.A. Times opinion article .) They think the effect is due to changes in the way the brain responds to insulin as a result of exposure to fructose. “Our study shows that a high fructose diet harms the brain as well as the body,” study senior author and UCLA professor Fernando Gomez-Pinilla said in a release about the finding, which was published in the Journal of Physiology (postdoc Rahul Agrawal was first author)

Bob Brickman spent months fighting a ticket he got last fall from a red-light traffic camera at Wilshire and Sepulveda boulevards in West Los Angeles. The 61-year-old from Playa Vista eventually decided to give up the fight and fork over the $476 fine. Now he's regretting paying every penny. City officials this week spotlighted a surprising revelation involving red-light camera tickets: Authorities cannot force violators who simply don't respond to pay them. For a variety of reasons, including the way the law was written, Los Angeles officials say the fines for ticketed motorists are essentially "voluntary" and there are virtually no tangible consequences for those who refuse to pay. The disclosure comes as the city is considering whether to drop the controversial photo enforcement program, with the City Council scheduled to vote on the matter Wednesday.

Bob Baffert and Wayne Lukas were sitting next to each other at a recent racing function when Baffert said to Lukas, "Everyone used to hate you. Now they hate me." It's as clear as a giant flowered hat, and just as ugly. At rowdy Churchill Downs today, the only thing more quietly despised than Bob Baffert will be a Breathalyzer. The 128th Kentucky Derby will feature 19 horses, 150,000 fans, and one villain. Baffert will saddle longshot War Emblem.

Los Angeles police will not pursue through the courts scores of motorists with unpaid tickets from the city's defunct red-light camera program. The city Police Commission voted this week to end its contract with the company that operated L.A.'s cameras until they were shut off last summer. And authorities are now planning to reassign a small group of officers who regularly appeared in court to testify in contested photo enforcement cases. With the cancellation of the contract, officers will no longer have easy access to the photo and video evidence that courts require.

Every year around this time millions of eggs are hard-boiled, artistically decorated and then thrown into the garbage. Frankly, that's probably just as well. Because most hard-boiled eggs are pretty terrible. The whites are rubbery, the yolks are pale and mealy and, even worse, surrounded by that sulfur-green ring of shame. Cooking hard-boiled eggs is easy; cooking them right is not. Unless you know what you're doing. Then it's as close to a foolproof no-brainer as you can get in the kitchen.

"Natural Selection," an intriguing and intelligent first effort from indie filmmaker Robbie Pickering, digs deep into the heart of Texas for its soulful tale of small town saints and sinners and a road trip to redemption. Laced with humor and regret, the film rests on a finely textured performance by Rachael Harris, a prolific character actress especially memorable as the harpy of a fiancée perpetually haranguing Ed Helms in "The Hangover. " Here she's dialed it down to a bare whisper for the 40ish Linda White, whose quiet life of desperation is about to be dissected.

What should the Lakers feel optimistic about against Oklahoma City? Mike Bresnahan: The Lakers actually showed some fire in their double-overtime victory over OKC last month. Can't remember a Lakers crowd ever getting that into a regular-season game. The Lakers' defense really showed me something in Game 7 against Denver. Not sure where it was the whole series, but the Lakers will have to employ it the entire time against OKC. Ben Bolch: The Lakers' 7-footers give them an advantage, provided they show up. Of course, that didn't always happen in the first round.

He had already been proclaimed "the Picasso of children's books" by Time magazine when Maurice Sendak, then in his 30s, wrote and illustrated "Where the Wild Things Are," a dark fantasy that became one of the 10 bestselling children's books of all time. Published in 1963, the book was a startling departure from the sweetness and innocence that then ruled children's literature. "Wild Things" tapped into the fears of childhood and sent its main character — an unruly boy in a wolf costume — into a menacing forest to tame the wild beasts of his imagination.

Build-a-Bear Workshop was introducing a line of stuffed animals called smallfrys and wanted to reach moms through Facebook. One video used in the online promotion showed a woman pulling up to a fast-food window. Her young daughter requests "a smallfry. " When her mom suggests a fruit cup or celery sticks, the daughter says, "Mom, order me a curly-haired bunny in a purple sequined bathing suit. " The 45-second smallfrys spot came not from a traditional advertising agency but from Poptent Inc., a "crowdsourced" video production studio that has built a global community of 50,000 writers, directors, cinematographers and animators to create commercials for Build-a-Bear, American Airlines, Dell, Intel, Jaguar, General Mills and others.

"Chinatown" writer Robert Towne has listed his estate on the Westside at $12.995 million. Built in 1926 and designed for grand entertaining, the restored English country-style mansion and guesthouse have seven bedrooms, nine bathrooms and 10,000 square feet of living space. The nearly three-quarter-acre property is wooded and includes a swimming pool, a rose garden and a spice garden. Towne, 77, won an Oscar for original screenplay in 1975 for the Jack Nicholson-starring film about land and water rights disputes.

Digby Wolfe, an Emmy Award-winning comedy writer who helped producer George Schlatter develop "Rowan & Martin's Laugh-In," a landmark TV series that became an overnight sensation in the late 1960s, has died. He was 82. Wolfe, who later became a professor of writing at the University of New Mexico, died of lung cancer Wednesday at his home in Albuquerque, said his wife, Patricia Mannion-Wolfe. The British-born Wolfe - an actor, writer, singer and comedian whose early career included writing for the BBC's satirical "That Was the Week That Was" and hosting an Australian TV variety show - moved to Los Angeles in the mid-'60s.

There's so much to praise in the blissful Broadway revival of "Follies," which opened Wednesday at the Ahmanson Theatre on the heels of its numerous Tony nominations, but let's pay homage first to the sheer sophistication of the show itself. After experiencing "Follies" again - an adult entertainment if ever there was one - I flat-out refuse to accept any more jukebox substitutes. One doesn't often talk about architecture when writing about musicals, but the most impressive thing about "Follies," beyond Stephen Sondheim's bejeweled score, is the ingenious way it is constructed.

It's been nearly 15 years since his last feature, but the influence of writer-director Whit Stillman, the indie auteur who assayed the social and emotional mores of an urban haute bourgeoisie with his films "Metropolitan," "Barcelona" and "The Last Days of Disco," has only grown, his talky nuance and spiky affection becoming more resonant with time. Which makes the new "Damsels in Distress" both such a welcome return and somewhat of an unexpected departure. Pitched as something of an old-fashioned campus comedy, the film, set to open in March, follows a group of coeds led by the determined Violet (Greta Gerwig)

A bio on NPR's website of its commentator Frank Deford notes that the magazine GQ christened him, quite simply, "the world's greatest sportswriter. " (Is he?) A story on ESPN's companion website, Grantland, referred to Deford as "a writer who had achieved legendary status by the age of 50. " (Did he?) OK. Maybe he is, and maybe he did. Wikipedia's entry for Sports Illustrated - if no one overnight has deleted it - alludes to an editor at that magazine who helped "launch the careers of such legendary writers as Frank Deford.

Hollywood's usual last-minute heroics don't factor in "Seeking a Friend for the End of the World. " In writer-director Lorene Scafaria's opening scene, a space mission to prevent a 70-mile-wide asteroid from hitting Earth fails spectacularly, giving everyone on the planet just three weeks to live. With the clock ticking, Dodge (Steve Carell) and Penny (Keira Knightley) try to figure out how to do just that. Romance and the apocalypse don't seem like obvious movie partners, which is precisely why Scafaria (who wrote "Nick and Norah's Infinite Play List")